The paper presents results of studies on the application of integrated data from airborne laser scanning (ALS) and satellite imagery (GeoEye-1) for the automatic mapping of vegetation (object-oriented image analysis) and to generate 3D spatial indices describing the structure of the vegetation. Created indices characterize the vertical diversity of vegetation (VDI Vegetation Diversity Index) and the amount of space filled by vegetation (FR Filling Ratio, V2A Volume to Area). In addition, the VV2BV index (Vegetation Volume to Built-up Volume) is expressing the ratio of volume of vegetation to volume of buildings. This indicator can be applied for valorization of built-up areas.